The encoding genes for factors VIII and IX are present in the long arm of chromosome X. Research has identified over 1,000 mutations in the genes encoding factor VIII and IX, and around 30% are due to spontaneous mutation (2). It is always due to a defect or mutation in the gene for the clotting factor. Hemophilia is usually an inherited condition and is caused by the deficiency of clotting factors in the blood. Hemophilia should be considered in the neonatal period in the case of unusual bleeding or in case of positive family history. The patient should receive treatment in a comprehensive treatment center where interprofessional services are offered at all times to the patients and their families. The principal aim of care should be to avoid and treat bleeding. The purpose of this document is to identify the etiology of hemophilia, review the evaluation of hemophilia, outline the treatment and management options available for hemophilia and describe interprofessional team strategies for improving care coordination and communication to advance hemophilia and improve outcomes. Hemophilia is the most common of the severe bleeding disorders and if not properly managed since early infancy can lead to chronic disease and lifelong disabilities. Nasse was the first to publish the genetic description of hemophilia in Nasse’s Law: which states that hemophilia is transmitted entirely by unaffected females to their sons (1). He then called them the “bleeders.” Hemophilia, as a word, was first documented by Johann Lukas Schonlein in his dissertation at the University of Zurich, Switzerland. He described and inherited bleeding disorder in several families where only males born from unaffected mothers are affected. The earliest description in modern history was documented by the American physician Dr. The earliest description of ancient history dates from second century AD in Babylonian Talmud about a woman who had lost her first two sons from circumcision. Hemophilia has often been called “the disease of the kings,” as is often described in the descent of Queen Victoria of England. Hemophilia, which means love (philia) of blood (hemo), is the most common severe hereditary hemorrhagic disorder. Educational grant provided by Women's Health and Education Center (WHEC). WHEC Practice Bulletin and Clinical Management Guidelines for healthcare providers.
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